Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial.
Identifieur interne : 000225 ( Main/Exploration ); précédent : 000224; suivant : 000226Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial.
Auteurs : Luisa Weiner [France] ; Fabrice Berna [France] ; Nathalie Nourry [France] ; François Severac [France] ; Pierre Vidailhet [France] ; Amaury C. Mengin [France]Source :
- Trials [ 1745-6215 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Betacoronavirus (génétique), Bibliothérapie (méthodes), Dépression (prévention et contrôle), Dépression (épidémiologie), Femelle (MeSH), France (épidémiologie), Humains (MeSH), Infections à coronavirus (psychologie), Infections à coronavirus (thérapie), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Mâle (MeSH), Pandémies (MeSH), Personnel de santé (psychologie), Pneumopathie virale (psychologie), Pneumopathie virale (thérapie), Pneumopathie virale (virologie), Pneumopathie virale (épidémiologie), Prestations des soins de santé (statistiques et données numériques), Prévalence (MeSH), Résilience psychologique (MeSH), Résultat thérapeutique (MeSH), Santé mentale (normes), Sujet âgé (MeSH), Thérapie cognitive (méthodes), Thérapie cognitive (statistiques et données numériques), Troubles de la veille et du sommeil (prévention et contrôle), Troubles de la veille et du sommeil (épidémiologie), Troubles de stress post-traumatique (prévention et contrôle), Troubles de stress post-traumatique (épidémiologie), Études cas-témoins (MeSH), Études prospectives (MeSH).
- MESH :
- génétique : Betacoronavirus.
- méthodes : Bibliothérapie, Thérapie cognitive.
- normes : Santé mentale.
- prévention et contrôle : Dépression, Troubles de la veille et du sommeil, Troubles de stress post-traumatique.
- psychologie : Infections à coronavirus, Personnel de santé, Pneumopathie virale.
- statistiques et données numériques : Prestations des soins de santé, Thérapie cognitive.
- thérapie : Infections à coronavirus, Pneumopathie virale.
- virologie : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Dépression, France, Infections à coronavirus, Pneumopathie virale, Troubles de la veille et du sommeil, Troubles de stress post-traumatique.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Pandémies, Prévalence, Résilience psychologique, Résultat thérapeutique, Sujet âgé, Études cas-témoins, Études prospectives.
- Wicri :
- geographic : France.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Betacoronavirus (genetics), Bibliotherapy (methods), COVID-19 (MeSH), Case-Control Studies (MeSH), Cognitive Behavioral Therapy (methods), Cognitive Behavioral Therapy (statistics & numerical data), Coronavirus Infections (epidemiology), Coronavirus Infections (psychology), Coronavirus Infections (therapy), Coronavirus Infections (virology), Delivery of Health Care (statistics & numerical data), Depression (epidemiology), Depression (prevention & control), Female (MeSH), France (epidemiology), Health Personnel (psychology), Humans (MeSH), Internet-Based Intervention (statistics & numerical data), Male (MeSH), Mental Health (standards), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (epidemiology), Pneumonia, Viral (psychology), Pneumonia, Viral (therapy), Pneumonia, Viral (virology), Prevalence (MeSH), Prospective Studies (MeSH), Resilience, Psychological (MeSH), SARS-CoV-2 (MeSH), Sleep Wake Disorders (epidemiology), Sleep Wake Disorders (prevention & control), Stress Disorders, Post-Traumatic (epidemiology), Stress Disorders, Post-Traumatic (prevention & control), Treatment Outcome (MeSH).
- MESH :
- geographic , epidemiology : France.
- epidemiology : Coronavirus Infections, Depression, Pneumonia, Viral, Sleep Wake Disorders, Stress Disorders, Post-Traumatic.
- genetics : Betacoronavirus.
- methods : Bibliotherapy, Cognitive Behavioral Therapy.
- prevention & control : Depression, Sleep Wake Disorders, Stress Disorders, Post-Traumatic.
- psychology : Coronavirus Infections, Health Personnel, Pneumonia, Viral.
- standards : Mental Health.
- statistics & numerical data : Cognitive Behavioral Therapy, Delivery of Health Care, Internet-Based Intervention.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adult, Aged, COVID-19, Case-Control Studies, Female, Humans, Male, Middle Aged, Pandemics, Prevalence, Prospective Studies, Resilience, Psychological, SARS-CoV-2, Treatment Outcome.
Abstract
BACKGROUND
The acknowledgment of the mental health toll of the COVID-19 epidemic in healthcare workers has increased considerably as the disease evolved into a pandemic status. Indeed, high prevalence rates of depression, sleep disorders, and post-traumatic stress disorder (PTSD) have been reported in Chinese healthcare workers during the epidemic peak. Symptoms of psychological distress are expected to be long-lasting and have a systemic impact on healthcare systems, warranting the need for evidence-based psychological treatments aiming at relieving immediate stress and preventing the onset of psychological disorders in this population. In the current COVID-19 context, internet-based interventions have the potential to circumvent the pitfalls of face-to-face formats and provide the flexibility required to facilitate accessibility to healthcare workers. Online cognitive behavioral therapy (CBT) in particular has proved to be effective in treating and preventing a number of stress-related disorders in populations other than healthcare workers. The aim of our randomized controlled trial study protocol is to evaluate the efficacy of the 'My Health too' CBT program-a program we have developed for healthcare workers facing the pandemic-on immediate perceived stress and on the emergence of psychiatric disorders at 3- and 6-month follow-up compared to an active control group (i.e., bibliotherapy).
METHODS
Powered for superiority testing, this six-site open trial involves the random assignment of 120 healthcare workers with stress levels > 16 on the Perceived Stress Scale (PSS-10) to either the 7-session online CBT program or bibliotherapy. The primary outcome is the decrease of PSS-10 scores at 8 weeks. Secondary outcomes include depression, insomnia, and PTSD symptoms; self-reported resilience and rumination; and credibility and satisfaction. Assessments are scheduled at pretreatment, mid-treatment (at 4 weeks), end of active treatment (at 8 weeks), and at 3-month and 6-month follow-up.
DISCUSSION
This is the first study assessing the efficacy and the acceptability of a brief online CBT program specifically developed for healthcare workers. Given the potential short- and long-term consequences of the COVID-19 pandemic on healthcare workers' mental health, but also on healthcare systems, our findings can significantly impact clinical practice and management of the ongoing, and probably long-lasting, health crisis.
TRIAL REGISTRATION
ClinicalTrials.gov NCT04362358 , registered on April 24, 2020.
DOI: 10.1186/s13063-020-04772-7
PubMed: 33087178
PubMed Central: PMC7576984
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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F" first="Fabrice" last="Berna">Fabrice Berna</name><affiliation wicri:level="3"><nlm:affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine, Université de Strasbourg, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Nourry, Nathalie" sort="Nourry, Nathalie" uniqKey="Nourry N" first="Nathalie" last="Nourry">Nathalie Nourry</name><affiliation wicri:level="4"><nlm:affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine, Université de Strasbourg, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Service de Pathologies Professionnelles et Médecine du Travail, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Pathologies Professionnelles et Médecine du Travail, Hôpitaux Universitaires de Strasbourg, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Severac, Francois" sort="Severac, Francois" uniqKey="Severac F" first="François" last="Severac">François Severac</name><affiliation wicri:level="3"><nlm:affiliation>Département de Santé Publique, GMRC, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département de Santé Publique, GMRC, Hôpitaux Universitaires de Strasbourg, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Laboratoire de Biostatistique et Informatique Médicale, iCUBE UMR 7357, Université de Strasbourg, Illkirch, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biostatistique et Informatique Médicale, iCUBE UMR 7357, Université de Strasbourg, Illkirch</wicri:regionArea><wicri:noRegion>Illkirch</wicri:noRegion><orgName type="university">Université de Strasbourg</orgName><placeName><settlement type="city">Strasbourg</settlement><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region></placeName></affiliation></author><author><name sortKey="Vidailhet, Pierre" sort="Vidailhet, Pierre" uniqKey="Vidailhet P" first="Pierre" last="Vidailhet">Pierre Vidailhet</name><affiliation wicri:level="3"><nlm:affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine, Université de Strasbourg, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Centre Régional Psychotraumatisme Grand Est, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Régional Psychotraumatisme Grand Est, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Mengin, Amaury C" sort="Mengin, Amaury C" uniqKey="Mengin A" first="Amaury C" last="Mengin">Amaury C. Mengin</name><affiliation wicri:level="3"><nlm:affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Centre Régional Psychotraumatisme Grand Est, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Régional Psychotraumatisme Grand Est, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author></analytic><series><title level="j">Trials</title><idno type="eISSN">1745-6215</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Betacoronavirus (genetics)</term><term>Bibliotherapy (methods)</term><term>COVID-19 (MeSH)</term><term>Case-Control Studies (MeSH)</term><term>Cognitive Behavioral Therapy (methods)</term><term>Cognitive Behavioral Therapy (statistics & numerical data)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (psychology)</term><term>Coronavirus Infections (therapy)</term><term>Coronavirus Infections (virology)</term><term>Delivery of Health Care (statistics & numerical data)</term><term>Depression (epidemiology)</term><term>Depression (prevention & control)</term><term>Female (MeSH)</term><term>France (epidemiology)</term><term>Health Personnel (psychology)</term><term>Humans (MeSH)</term><term>Internet-Based Intervention (statistics & numerical data)</term><term>Male (MeSH)</term><term>Mental Health (standards)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (psychology)</term><term>Pneumonia, Viral (therapy)</term><term>Pneumonia, Viral (virology)</term><term>Prevalence (MeSH)</term><term>Prospective Studies (MeSH)</term><term>Resilience, Psychological (MeSH)</term><term>SARS-CoV-2 (MeSH)</term><term>Sleep Wake Disorders (epidemiology)</term><term>Sleep Wake Disorders (prevention & control)</term><term>Stress Disorders, Post-Traumatic (epidemiology)</term><term>Stress Disorders, Post-Traumatic (prevention & control)</term><term>Treatment Outcome (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Betacoronavirus (génétique)</term><term>Bibliothérapie (méthodes)</term><term>Dépression (prévention et contrôle)</term><term>Dépression (épidémiologie)</term><term>Femelle (MeSH)</term><term>France (épidémiologie)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (psychologie)</term><term>Infections à coronavirus (thérapie)</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Personnel de santé (psychologie)</term><term>Pneumopathie virale (psychologie)</term><term>Pneumopathie virale (thérapie)</term><term>Pneumopathie virale (virologie)</term><term>Pneumopathie virale (épidémiologie)</term><term>Prestations des soins de santé (statistiques et données numériques)</term><term>Prévalence (MeSH)</term><term>Résilience psychologique (MeSH)</term><term>Résultat thérapeutique (MeSH)</term><term>Santé mentale (normes)</term><term>Sujet âgé (MeSH)</term><term>Thérapie cognitive (méthodes)</term><term>Thérapie cognitive (statistiques et données numériques)</term><term>Troubles de la veille et du sommeil (prévention et contrôle)</term><term>Troubles de la veille et du sommeil (épidémiologie)</term><term>Troubles de stress post-traumatique (prévention et contrôle)</term><term>Troubles de stress post-traumatique (épidémiologie)</term><term>Études cas-témoins (MeSH)</term><term>Études prospectives (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>France</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Depression</term><term>Pneumonia, Viral</term><term>Sleep Wake Disorders</term><term>Stress Disorders, Post-Traumatic</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Bibliotherapy</term><term>Cognitive Behavioral Therapy</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Bibliothérapie</term><term>Thérapie cognitive</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Santé mentale</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Depression</term><term>Sleep Wake Disorders</term><term>Stress Disorders, Post-Traumatic</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Dépression</term><term>Troubles de la veille et du sommeil</term><term>Troubles de stress post-traumatique</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Personnel de santé</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Coronavirus Infections</term><term>Health Personnel</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Mental Health</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Cognitive Behavioral Therapy</term><term>Delivery of Health Care</term><term>Internet-Based Intervention</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Prestations des soins de santé</term><term>Thérapie cognitive</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Dépression</term><term>France</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>Troubles de la veille et du sommeil</term><term>Troubles de stress post-traumatique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>COVID-19</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Prevalence</term><term>Prospective Studies</term><term>Resilience, Psychological</term><term>SARS-CoV-2</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Pandémies</term><term>Prévalence</term><term>Résilience psychologique</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Études cas-témoins</term><term>Études prospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>The acknowledgment of the mental health toll of the COVID-19 epidemic in healthcare workers has increased considerably as the disease evolved into a pandemic status. Indeed, high prevalence rates of depression, sleep disorders, and post-traumatic stress disorder (PTSD) have been reported in Chinese healthcare workers during the epidemic peak. Symptoms of psychological distress are expected to be long-lasting and have a systemic impact on healthcare systems, warranting the need for evidence-based psychological treatments aiming at relieving immediate stress and preventing the onset of psychological disorders in this population. In the current COVID-19 context, internet-based interventions have the potential to circumvent the pitfalls of face-to-face formats and provide the flexibility required to facilitate accessibility to healthcare workers. Online cognitive behavioral therapy (CBT) in particular has proved to be effective in treating and preventing a number of stress-related disorders in populations other than healthcare workers. The aim of our randomized controlled trial study protocol is to evaluate the efficacy of the 'My Health too' CBT program-a program we have developed for healthcare workers facing the pandemic-on immediate perceived stress and on the emergence of psychiatric disorders at 3- and 6-month follow-up compared to an active control group (i.e., bibliotherapy).</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>Powered for superiority testing, this six-site open trial involves the random assignment of 120 healthcare workers with stress levels > 16 on the Perceived Stress Scale (PSS-10) to either the 7-session online CBT program or bibliotherapy. The primary outcome is the decrease of PSS-10 scores at 8 weeks. Secondary outcomes include depression, insomnia, and PTSD symptoms; self-reported resilience and rumination; and credibility and satisfaction. Assessments are scheduled at pretreatment, mid-treatment (at 4 weeks), end of active treatment (at 8 weeks), and at 3-month and 6-month follow-up.</p></div><div type="abstract" xml:lang="en"><p><b>DISCUSSION</b></p><p>This is the first study assessing the efficacy and the acceptability of a brief online CBT program specifically developed for healthcare workers. Given the potential short- and long-term consequences of the COVID-19 pandemic on healthcare workers' mental health, but also on healthcare systems, our findings can significantly impact clinical practice and management of the ongoing, and probably long-lasting, health crisis.</p></div><div type="abstract" xml:lang="en"><p><b>TRIAL REGISTRATION</b></p><p>ClinicalTrials.gov NCT04362358 , registered on April 24, 2020.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33087178</PMID><DateCompleted><Year>2020</Year><Month>11</Month><Day>03</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>18</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1745-6215</ISSN><JournalIssue CitedMedium="Internet"><Volume>21</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>Oct</Month><Day>21</Day></PubDate></JournalIssue><Title>Trials</Title><ISOAbbreviation>Trials</ISOAbbreviation></Journal><ArticleTitle>Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial.</ArticleTitle><Pagination><MedlinePgn>870</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s13063-020-04772-7</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The acknowledgment of the mental health toll of the COVID-19 epidemic in healthcare workers has increased considerably as the disease evolved into a pandemic status. Indeed, high prevalence rates of depression, sleep disorders, and post-traumatic stress disorder (PTSD) have been reported in Chinese healthcare workers during the epidemic peak. Symptoms of psychological distress are expected to be long-lasting and have a systemic impact on healthcare systems, warranting the need for evidence-based psychological treatments aiming at relieving immediate stress and preventing the onset of psychological disorders in this population. In the current COVID-19 context, internet-based interventions have the potential to circumvent the pitfalls of face-to-face formats and provide the flexibility required to facilitate accessibility to healthcare workers. Online cognitive behavioral therapy (CBT) in particular has proved to be effective in treating and preventing a number of stress-related disorders in populations other than healthcare workers. The aim of our randomized controlled trial study protocol is to evaluate the efficacy of the 'My Health too' CBT program-a program we have developed for healthcare workers facing the pandemic-on immediate perceived stress and on the emergence of psychiatric disorders at 3- and 6-month follow-up compared to an active control group (i.e., bibliotherapy).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Powered for superiority testing, this six-site open trial involves the random assignment of 120 healthcare workers with stress levels > 16 on the Perceived Stress Scale (PSS-10) to either the 7-session online CBT program or bibliotherapy. The primary outcome is the decrease of PSS-10 scores at 8 weeks. Secondary outcomes include depression, insomnia, and PTSD symptoms; self-reported resilience and rumination; and credibility and satisfaction. Assessments are scheduled at pretreatment, mid-treatment (at 4 weeks), end of active treatment (at 8 weeks), and at 3-month and 6-month follow-up.</AbstractText><AbstractText Label="DISCUSSION" NlmCategory="CONCLUSIONS">This is the first study assessing the efficacy and the acceptability of a brief online CBT program specifically developed for healthcare workers. Given the potential short- and long-term consequences of the COVID-19 pandemic on healthcare workers' mental health, but also on healthcare systems, our findings can significantly impact clinical practice and management of the ongoing, and probably long-lasting, health crisis.</AbstractText><AbstractText Label="TRIAL REGISTRATION" NlmCategory="BACKGROUND">ClinicalTrials.gov NCT04362358 , registered on April 24, 2020.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Weiner</LastName><ForeName>Luisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France. weiner.l@gmail.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire de Psychologie des Cognitions, Université de Strasbourg, 12 rue goethe, 67000, Strasbourg, France. weiner.l@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berna</LastName><ForeName>Fabrice</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nourry</LastName><ForeName>Nathalie</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Service de Pathologies Professionnelles et Médecine du Travail, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Severac</LastName><ForeName>François</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Département de Santé Publique, GMRC, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire de Biostatistique et Informatique Médicale, iCUBE UMR 7357, Université de Strasbourg, Illkirch, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vidailhet</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculté de Médecine, Université de Strasbourg, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre Régional Psychotraumatisme Grand Est, Strasbourg, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mengin</LastName><ForeName>Amaury C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Pôle de Psychiatrie, Santé Mentale et Addictologie, Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM U1114 Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie, Strasbourg, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre Régional Psychotraumatisme Grand Est, Strasbourg, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList 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last="Berna">Fabrice Berna</name><name sortKey="Mengin, Amaury C" sort="Mengin, Amaury C" uniqKey="Mengin A" first="Amaury C" last="Mengin">Amaury C. Mengin</name><name sortKey="Mengin, Amaury C" sort="Mengin, Amaury C" uniqKey="Mengin A" first="Amaury C" last="Mengin">Amaury C. Mengin</name><name sortKey="Mengin, Amaury C" sort="Mengin, Amaury C" uniqKey="Mengin A" first="Amaury C" last="Mengin">Amaury C. Mengin</name><name sortKey="Nourry, Nathalie" sort="Nourry, Nathalie" uniqKey="Nourry N" first="Nathalie" last="Nourry">Nathalie Nourry</name><name sortKey="Nourry, Nathalie" sort="Nourry, Nathalie" uniqKey="Nourry N" first="Nathalie" last="Nourry">Nathalie Nourry</name><name sortKey="Severac, Francois" sort="Severac, Francois" uniqKey="Severac F" first="François" last="Severac">François Severac</name><name sortKey="Severac, Francois" sort="Severac, Francois" uniqKey="Severac F" first="François" last="Severac">François Severac</name><name sortKey="Vidailhet, Pierre" sort="Vidailhet, Pierre" uniqKey="Vidailhet P" first="Pierre" last="Vidailhet">Pierre Vidailhet</name><name sortKey="Vidailhet, Pierre" sort="Vidailhet, Pierre" uniqKey="Vidailhet P" first="Pierre" last="Vidailhet">Pierre Vidailhet</name><name sortKey="Vidailhet, Pierre" sort="Vidailhet, Pierre" uniqKey="Vidailhet P" first="Pierre" last="Vidailhet">Pierre Vidailhet</name><name sortKey="Vidailhet, Pierre" sort="Vidailhet, Pierre" uniqKey="Vidailhet P" first="Pierre" last="Vidailhet">Pierre Vidailhet</name><name sortKey="Weiner, Luisa" sort="Weiner, Luisa" uniqKey="Weiner L" first="Luisa" last="Weiner">Luisa Weiner</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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